Labuda, Damian, Ph.D.

Coordonnées

Centre de recherche, CHU Sainte-Justine
T 514 345-4931 #3586
345-4931 #3282 (sec.)
F 514 345-4731
damian.labuda@umontreal.ca

Axes de recherche

  • Génomique
  • Bioinformatique
  • Génétique humaine et maladies génétiques

Description de la recherche

  • Génétique des populations et génétique évolutionnaire
  • L’évolution et la diversité du génome humain – l’origine et l’histoire génétique des populations humaines
  • Analyse expérimentale et statistique –  approches formelles en génétique des populations et en évolution génomique – la bioinformatique.

Research axis

  • Genomic
  • Bioinformatics
  • Human genetics and genetic diseases

Research description

  • Evolutionary and population genetics
  • Evolution and variability of the human genome – origins and genetic history of human populations
  • Experimental and statistical analysis – formal approaches in population genetics and in evolutionary genomics – bioinformatics

Publications

  • Moreau C, Bherer C, Vézina H, Jomphe M, Labuda D, Excoffier L (2011) Deep human genealogies reveal a selective advantage to be on an expanding wave front. Science  334 (6059):1148-50. Epub 2011 Nov 3.
  • Yotova V, Lefebvre J F, Moreau C, Gbeha E, Hovhannesyan K, Bourgeois S, Bédarida S,  Azevedo L, Amorim A, Sarkisian T, Avogbe P, Chabi N, Dicko M H, Kou E S, Amouzou S, Sanni A, Roberts-Thomson J, Boettcher B, Scott RJ, Labuda D (2011) Modern Humans Encounter with Neandertals at the Gate of their out of-Africa Migration. Mol Biol Evol 2011 28(7):1957-62
  • Labuda D, Lefebvre JF, Nadeau P and Roy-Gagnon M-H (2009) Female to male breeding ratio in modern humans. Am J Hum Genet. 2010 86(3):353-63 and 86(6): 982
  • Zietkiewicz E, Yotova V, Gehl D, Wambach T, Arrieta I, Batzer M, Cole DEC, Hechtman P, Kaplan F, Modiano D, Moisan J-P, Michalski R and Labuda D (2003) Haplotypes in the dystrophin DNA segment point to a mosaic origin of modern humans’ diversity. Am J Hum Genet. 73:994-1015
  • Gilbert N and Labuda D (1999) CORE-SINEs: Eukaryotic short interspersed retroposing elements with common sequence motif. Proc Natl Acad Sci USA 96:2869-2874.