{"id":3634,"date":"2012-01-23T11:16:08","date_gmt":"2012-01-23T16:16:08","guid":{"rendered":"https:\/\/biomol.umontreal.ca\/research\/professors\/kmita-marie-phd\/"},"modified":"2013-08-16T15:57:45","modified_gmt":"2013-08-16T19:57:45","slug":"kmita-marie-phd","status":"publish","type":"page","link":"https:\/\/biomol.umontreal.ca\/en\/research\/les-professeurs\/kmita-marie-phd\/","title":{"rendered":"Kmita, Marie, Ph.D."},"content":{"rendered":"

Directrice de l\u2019unit\u00e9 de Recherche en G\u00e9n\u00e9tique et D\u00e9veloppement<\/p>\n

Coordonn\u00e9es<\/h3>\n

Institut de Recherches Cliniques de Montr\u00e9al
\n110, avenue des Pins Ouest
\nMontr\u00e9al (Qu\u00e9bec) H2W1R7
\nmarie.kmita@ircm.qc.ca<\/a>
\nT<\/strong> 514 987-5749
\nF<\/strong> 514-987-5740<\/p>\n\n

\n

Axes de recherche<\/h2>\n
    \n
  • D\u00e9veloppement et diff\u00e9rentiation tissulaire<\/li>\n
  • G\u00e9nomique<\/li>\n
  • G\u00e9n\u00e9tique humaine et maladies g\u00e9n\u00e9tiques<\/li>\n<\/ul>\n

    Description de la recherche<\/h2>\n

    Les travaux du laboratoire visent \u00e0 identifier les m\u00e9canismes g\u00e9n\u00e9tiques qui assurent le d\u00e9veloppement de l\u2019embryon en utilisant la souris comme mod\u00e8le. Nous cherchons en particulier caract\u00e9riser les fonctions de la famille des g\u00e8nes Hox ainsi que les m\u00e9canismes qui sont impliqu\u00e9s dans la r\u00e9gulation transcriptionnelle de ces g\u00e8nes. Nos \u00e9tudes sont bas\u00e9es sur des approches g\u00e9n\u00e9tiques chez la souris et impliquent \u00e9galement des techniques de pointe en g\u00e9nomique. Par ces \u00e9tudes nous cherchons \u00e0 contribuer \u00e0 une meilleure compr\u00e9hension des causes de malformations cong\u00e9nitales chez l\u2019homme.
    \n<\/div>\n

    \n

    Research axis<\/h2>\n
      \n
    • Development and tissue differentiation<\/li>\n
    • Genomic<\/li>\n
    • Human genetics and genetic diseases<\/li>\n<\/ul>\n

      Research description<\/h2>\n

      The research focus of the lab is to identify genetics mechanisms ensuring proper embryonic development using mice as model system. In particular, our work is aimed at characterizing the function of the Hox gene family as well as transcriptional regulatory mechanisms controlling Hox genes\u2019 expression. Our studies are based on mouse genetics and also involve state-of-the-art genomic techniques. Through these studies, our aim is to help unraveling molecular events responsible for congenital malformations in humans.<\/p>\n<\/div>\n

       <\/p>\n","protected":false},"excerpt":{"rendered":"

      Directrice de l\u2019unit\u00e9 de Recherche en G\u00e9n\u00e9tique et D\u00e9veloppement Coordonn\u00e9es Institut de Recherches Cliniques de Montr\u00e9al 110, avenue des Pins Ouest Montr\u00e9al (Qu\u00e9bec) H2W1R7 marie.kmita@ircm.qc.ca T 514 987-5749 F 514-987-5740 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3557,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-3634","page","type-page","status-publish","hentry"],"yoast_head":"\nKmita, Marie, Ph.D. - Programmes de biologie mol\u00e9culaire<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biomol.umontreal.ca\/en\/research\/les-professeurs\/kmita-marie-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kmita, Marie, Ph.D. - 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